Searchable abstracts of presentations at key conferences in endocrinology

ea0099oc12.2 | Oral Communications 12: Diabetes, Obesity, Metabolism and Nutrition | Part II | ECE2024

Intestinimonas butyriciproducens as a new preventive therapy for type 2 diabetes: a proof of concept randomized controlled trial

Antoniotti Valentina , Caputo Marina , Mollero Edoardo Luigi Maria , Antonioli Alessandro , TIni Sabrina , Manfredi Marcello , Bona Elisa , Pane Marco , Amoruso Angela , De Prisco Annachiara , Gul Sahin , Bui Nam , Seegers Jos , De Vos Willem M , Aimaretti Gianluca , Prodam Flavia

Background: The incidence of type 2 Diabetes Mellitus (T2D) is increasing worldwide. Prevention is possible by changing lifestyle but itÂ’s not effective alone in real life, due to poor compliance over time. New strategies are necessary, mostly for high-risk individuals. Therapeutic microbiology is a further proposed target, and butyrate-producing bacteria can improve metabolic parameters in obese patients. Our study aims to evaluate the effect of Intestinimonas butyri...